A patient walks into a thoracic surgery consultation with a small lung tumor, stage I on every scan, and every conventional ...

Panelists discuss how early relapse in standard-risk patients represents a failure of current risk assessment methods and may require advanced sequencing technologies to identify hidden high-risk ...

Serial circulating tumor DNA analysis can demonstrate rapid clonal dynamics that evolve during response and resistance to both standard chemotherapy and targeted therapy of BRAF-mutant colon cancer ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

Despite substantial progress in cancer treatment, durable benefit is still frequently limited by the ability of tumors to adapt under therapeutic pressure.

Using lung cancer biospecimens from the Sherlock-Lung study, an international team led by National Institutes of Health (NIH) researchers, identified key factors that drive tumor evolution and ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...

The way in which blood stem cells evolve over a lifespan differs greatly between humans and mice, new research reveals. The findings provide a new understanding of the critical factors that influence ...